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Transepithelial phototherapeutic keratectomy is a safe and effective therapy for recurrent corneal erosions. Additional treatment with autologous serum eyedrops can support the healing process following corneal erosions and t-PTK and can be given as a long-term artificial tear treatment.

CFF decreased in non-exsudative and exsudative AMD. CFF is not able to distinguish between AMD eyes and healthy eyes of equal visual acuity, and therefore is not applicable as a possible diagnostic test.

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Laser photoablation using UV or JR lasers is known to trigger a photo acoustic event. Different target materials can be discriminated by analyzing the photoacoustic signal. In vitro measurements ofNCPAS have revealed the necessity to integrate a number of variable elements (tissue hydration, fluence, laser beam diameter, distance to microphone, etc.). This study defines the parameters needed for the initiation of a seiflearning system for target material recognition. A UV Excimer laser (X=193 nm; Summit Technology, UV 200L) was used to ablate organic polymers (PMMA, PA, PVC), normal and porcine corneal scar tissue, and human cornea in vivo. NCPAS was performed using a microphone (up to 200 kHz) as a detector. During photoablation, the acoustic signal was analyzed by a multiport A/D IBM PC based digital oscilloscope. The data obtained were imported into a Matlab language program and analyzed.NCPAS allows the discrimination of different materials by a characteristically frequency shift of the photoacoustic signal. Detection and online material recognition using NCPAS is a step on the way to a laser control, based on an artificial neuronal network.