Abstract. Background: Total joint arthroplasties continue to increase as do periprosthetic joint
infections (PJIs). Ultrasound-guided aspiration can yield useful synovial
fluid for analysis while avoiding radiation exposure. This study presents a
high-yield, ultrasound-guided technique with analysis of aspiration results.
Methods: All consecutive ultrasound-guided aspirations of hip arthroplasties
performed from May 2016 through to April 2019 were retrospectively reviewed.
Patient demographic information, component specifics, presence of draining
sinus, and inflammatory markers were recorded. Results of aspiration
including volume, appearance, lavage use, synovial fluid differential
leukocyte count, synovial neutrophil percent, and culture results were
recorded. Surgical results, specimen cultures, and surgeon description of
purulence were recorded. Aspiration results were compared to the surgical
specimen results in all patients who underwent reoperations.
Results: Review of 349 hip aspirations demonstrated accuracy of 87 %, sensitivity
of 83 %, specificity of 89 %, positive predictive value of 79 %, and negative
predictive value 91 %. Surgical and aspiration cultures matched in 81 % of cases.
Bloody aspirates and aspirates obtained after lavage had less
accuracy at 69 % and 60 %, respectively. Specificity was 100 % for
cultures obtained with lavage and 91 % for bloody aspirates. Synovial
leukocyte count and neutrophil percentage was obtained in
85 % of aspirations, and cultures were obtained in 98 % of aspirates. Contamination rate
was 2 %.
Conclusion: Ultrasound-guided aspirations aid in the diagnosis of PJI. The use of lavage
to obtain fluid is helpful when aspiration cultures are positive. Bloody
aspirates are less accurate but have high specificity. A low contamination
rate and 88 % accuracy results with this meticulous technique.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.