Background: Diabetes and depression are among diseases highly associated with life style, urbanism, and industrialization. The concomitance of the two of them costs the patients many years of their lives. Many researchers have been done on the outbreak of depression among diabetics in Iran. The principal purpose of this study is to determine the outbreak of depression among diabetics using the Meta-analysis method. Methods: This study is a systematic review. The prevalence rate of depression among diabetics estimation was determined using Meta-analysis method on the data extracted from English and Persian data bases. To analyze the information obtained, we used STATA 11.2 and the random effect model. Results: Among 32 eligible researches 7135 patients with type I and II diabetes were chosen for this study. Using Beck's self-report scale 65% of the cases shown mild to severe symptoms of depression. 64% of the patients were female and the prevalence rate of depression was reported 71.3% in the female and 60.3% in the male cases. Conclusion:The prevalence rate of depression among Iranian diabetics is higher in comparison with other countries. Considering the fact that the concomitance of the two of these diseases results in a raise in medical costs, it is recommended to the doctors to check for depression symptoms in diabetics and recommend health solutions to the patient and the one accompanying them.

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