BACKGROUND: Sciatica is a radiating pain that is caused due to the impingement in bony structures. Cupping is a simple application of quick, vigorous, rhythmical strokes to stimulate muscles and it's also helpful in the treatment of aches and pains associated with various disorders. AIM AND OBJECTIVES: AIM:To nd out the effectiveness of cupping therapy on nerve conduction velocity in sciatica. OBJECTIVES:To nd out the effect of cupping therapy on NCV in sciatica. To compare the experimental group to the control group. METHOD: Thirty patients were selected based on inclusion and exclusion criteria. The details of the treatment were explained to the subjects and written consent was taken from the patients. They were treated with cupping therapy for three alternative days/week, the patient was reassessed with NPRS and NCV after 4 weeks. RESULTS: The data was analyzed using SPSS version 22.0. A parametric test was used within the group analysis. A signicant improvement in pain and functional status of the nerve was found after 4 weeks. Greater statistically signicant improvement was seen in Group-A (p-value is 0.00) as compared to Group-B CONCLUSIONS: Cupping therapy is effective to reduce pain and improvement in functional status of nerves in Sciatica patients.