To design a lyophilizer plant in Guangzhou, the author of this paper used a solar energy absorption refrigeration system and a waste heat of solar absorption refrigeration system. Using Trnsys software, the simulation results show that the solar assurance rate of 74.96% on July 28th can save coal quantity of about 236.8 kg, a solar assurance rate of 53.48% in July can save coal quantity of about 4790.9 kg, and an annual solar assurance rate of 39.06% can save about 40657.1 kg, and each have good environmental benefits.