In order to improve the communication efficiency while ensuring the security of communication information, this paper proposes a design and research method of a computer information security communication method by introducing data encryption technology. A new communication method is proposed through the construction of computer information security communication transmission model, computer information communication user identity authentication, communication information data encryption and decryption processing based on data encryption technology, and computer secondary communication key update. The experimental results show that the new communication method and ZigBee-based communication method are applied to the same communication environment through comparative experiments. The addition of encryption time and decryption time of the experimental group can be basically controlled within 70 ms, while the addition of encryption time and decryption time of the control group exceeds 70 ms, which verifies that the new communication method has higher security and communication efficiency. The introduction of data encryption technology in the actual information communication process can provide guarantee conditions for information security.