Minks are raised in many countries and have transmitted severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) to humans. However, the biologic properties of SARS-CoV-2 in minks are largely unknown. Here, we investigated and found that SARS-CoV-2 replicates efficiently in both the upper and lower respiratory tracts, and transmits efficiently in minks via respiratory droplets; pulmonary lesions caused by SARS-CoV-2 in minks are similar to those seen in humans with COVID-19. We further found that a spike protein-based subunit vaccine largely prevented SARS-CoV-2 replication and lung damage caused by SARS-CoV-2 infection in minks. Our study indicates that minks are a useful animal model for evaluating the efficacy of drugs or vaccines against COVID-19 and that vaccination is a potential strategy to prevent minks from transmitting SARS-CoV-2.

Schoolteachers worldwide are facing stressful work conditions with heavy responsibilities. Stress may contribute to psychological disorders and physical health issues. The purposes of this study were (1) to investigate whether both challenge and hindrance stressors are positively associated with emotional exhaustion among Chinese schoolteachers and (2) to examine whether perceived servant leadership moderates the effects of challenge and hindrance stressors on emotional exhaustion. This study was cross-sectional in nature. A sample of 2636 schoolteachers was elicited from schools in South China. Research data were collected in the fall semester of 2019 via WeChat®. Descriptive statistics and inter-correlations were conducted using SPSS 21. Confirmatory factor analysis was applied to test measurement models to determine convergent and discriminant validities using Mplus 7.4. Hierarchical multiple regression was performed to test proposed hypotheses using SPSS 21. The study results demonstrated that both challenge and hindrance stressors were positively related to emotional exhaustion among schoolteachers in Chinese schools. It was also indicated that, while perceived servant leadership buffers the relationship between challenge stressor and emotional exhaustion, it enhances the relationship between hindrance stressor and emotional exhaustion. Implications and limitations are also provided.

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In order to analyse the prevalence of cat viral diseases in China, including feline parvovirus (FPV), feline calicivirus (FCV), feline herpesvirus 1 (FHV-1), feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV) and feline infectious peritonitis virus (FIPV), a total of 1,326 samples of cats from 16 cities were investigated from 2016 to 2019. Collectively, 1,060 (79.9%) cats were tested positive for at least one virus in nucleotide detection, and the positive rates of cat exposure to FeLV, FPV, FHV-1,

Feline panleukopenia virus (FPV) and canine parvovirus (CPV) infections are highly contagious and cause serious enteric diseases, with high fatality rates of cats and dogs. Given the importance of cats as a potential source of genetic diversity for parvoviruses, parvovirus strains detected in cats with gastroenteritis signs were analysed, and molecular characterisation, sequence analysis and phylogeny were evaluated on the VP2 gene. The results showed that FPV, new CPV-2a, and CPV-2 are co-circulating in the cat population in Henan province of China. Moreover, CPV-2 strains (F2016020, and F2016021) with Ser297Ala substitution in VP2 protein was for the first time detected in cats with clinical gastroenteritis. This study provided new important findings about the evolutionary of parvovirus infection in domestic cats.