With the prevalence of a circular economy, extended producer responsibility, and the maturity of intelligent manufacturing technology, Design for Remanufacture (DfRem) has become a new driving force for the profitability of the modern supply chain. DfRem activities occur at the stage of new product design but have a significant impact on subsequent remanufacturing operations. Based on the closed-loop supply chain operation systems with DfRem, we systematically explored the impact of DfRem on supply chain operation decisions through a case study and modeling analysis and built up a modeling research framework of DfRem-driven closed-loop supply chain (CLSC) operation decision-making. Our research identified DfRem-driven model design elements and discussed the modeling of DfRem-driven investment decision problems, involving different approaches to obtain DfRem investment (i.e., DfRem-driven horizontal or vertical supply chain cooperation) and the ownership of DfRem-level decision-making rights. Moreover, the DfRem-driven two-stage and multi-period modeling processes are elaborated in detail. The aim of this paper is to provide other scholars with a more comprehensive understanding of DfRem research issues, and to establish an integrated DfRem-driven research framework for subsequent scholars to better conduct modeling research on DfRem.

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