In order to study the influencing factors of cross-cultural communicative competence of English majors under mobile Internet, firstly, we made an empirical study on cross-cultural communication teaching for English majors. Then, we performed a comparative experiment between the mobile Internet-assisted high school English cross-cultural communication teaching model and the traditional teacher culture teaching-based teaching model. Finally, through questionnaires, informal interviews, and teachers’ observation of the teaching process, this paper aims to make an empirical study on the feasibility and effectiveness of mobile Internet assisted foreign language teachers in cultivating students’ awareness and ability of cross-cultural communication, so as to provide a basis for the follow-up research of cross-cultural communication teaching for English majors. The experimental results show that 93.4% of the students are satisfied with the mobile network-assisted English cross-cultural communication teaching model, and the integration of mobile network technology into English cross-cultural communication teaching has brought great changes to the teaching process. Compared with the traditional teaching mode of “chalk and blackboard,” multimedia organically integrates text, pictures, audio, video, and network, which greatly attracts the attention of teachers and students.