Elderly patients and those with a prolonged duration of symptoms had worse outcomes following surgical intervention for AMI. A high index of suspicion with prompt diagnostic evaluation may reduce time delay prior to surgical intervention, which may lead to improved patient survival. Aggressive surgical intervention should be performed as promptly as possible in patients once the diagnosis of AMI is made.
Hemodynamic depression, including hypotension and bradycardia, is frequent after CAS. However, CAS-induced hemodynamic depression is rare in patients with postendarterectomy stenosis. Patients with compromised ejection fraction and increased age are at a higher risk of presenting with CAS-induced hemodynamic instability, and persistent hypotension after CAS is associated with an increased postprocedural complication rate.
Purpose
Thoracic endovascular aortic aneurysm repair (TEVAR) has become a
mainstay of therapy for aneurysmal and other disorders of the thoracic
aorta. The purpose of this narrative review article is to summarize the
current literature on the risk factors, pathophysiology of spinal cord
injury (SCI) following TEVAR, and to discuss various intraoperative
monitoring and treatment strategies.
Source
Articles considered in this review were identified through PubMed
using the following search terms: thoracic aortic aneurysm, TEVAR,
paralysis+TEVAR, risk factors+TEVAR, spinal cord
ischemia+TEVAR, neuromonitoring+thoracic aortic aneurysm,
spinal drain, cerebrospinal fluid drainage, treatment of spinal cord
ischemia.
Principal findings
Spinal cord injury continues to be a challenging complication after
TEVAR. Its incidence after TEVAR is not significantly reduced compared to
open TAAA repair. However, compared to open procedures, delayed
paralysis/paresis is the predominant presentation of SCI after TEVAR. The
pathophysiology of SCI is complex and remains not fully understood though
the evolving concept of the importance of the spinal cord’s
collateral blood supply network and its imbalance after TEVAR is emerging as
a leading factor in the development of SCI. Cerebrospinal fluid drainage,
optimal blood pressure management, and newer surgical techniques are
important components of the most current spinal cord protection
strategies.
Conclusion
Further experimental and clinical research is needed to aid in the
discovery of novel neuroprotective strategies for protection and treatment
of SCI following TEVAR.
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