Background: Cesarean Section incidence increase globally during past three decades. It's also the most frequent major abdominal surgery. Changing surgical glove during cesarean section post placental delivery may decrease bacterial transfer to the wound and decrease wound infection post cesarean section. Aim of the work:To study ,investigate and evaluate the clinical effect of Post cesarean section wound complications after changing surgical gloves Intra-operative post placental delivery in cesarean section and related to Evidence based. Patients and methods: Retrospective study was included 200 pregnant women presenting to the outpatient clinic at El Hussein Hospital and planned to undergo elective cesarean section according to the inclusion and exclusion criteria and had divided into two groups. Results: According to wound complication, among cases, 0 (0%) were Seroma, 0 (0%) were Hematoma, 0 (0%) were Separation, 1 (1%) 0 (0%) were Wound infection, 0 (0%) Skin infection, 0 (0%) were Endometritis, 0 (0%) were Febrile morbidity. Among control group, 5 (5%) were Seroma, 0 (0%) were Hematoma, 10 (10%) were Separation 5 (5%) ، 5 (5%) were Wound infection, 03 (3%) Skin infection, 0 (0%) were Endometritis, 5 (5%) were Febrile morbidity. There was statistically important difference between studied cases as regard seroma, separation, wound infection, skin infection and febrile morbidity. Conclusion: Changing gloves during C-S was linked to a lower risk of infection at the incisional surgical site, as well as a reduction in postoperative febrile morbidity.