Presented data was gathered from a local rehabilitation & caring center in Ahwaz city, southwest Iran end-2017. Data was classified in the six sections upon two predictors i.e. years of imprisonments and Injecting Drug Users (IDUs) to predict three blood infectious diseases i.e. HIV-Aids, Hepatitis B Virus (HBV), & Hepatitis C Virus (HCV). Each section jointly includes the following: tables of raw data, input data concerning false & true positive fractions (18 tables), scatter graph concerning false positive fractions (FPF) & true positive fractions (TPF) (6 graphs), and six ROC curves. The full access to data set is available at Mendeley data repository via doi:10.17632/6s9yzm7hr7.110.17632/6s9yzm7hr7.1.