99mTc-MIBI has significant uptake in the active tuberculosis lesions and can be used to differentiate between active and inactive tuberculosis. The SPECT method is especially useful because of its higher sensitivity.

Tc-EDDA-tricine-HYNIC-Tyr-octreotate scintigraphy may help to differentiate between active and inactive pulmonary tuberculosis. SPECT imaging and semiquantitative evaluation are indispensable for increasing the diagnostic yield of this method. Larger studies are needed to corroborate our results.