The paper proposed a practice teaching mode by making analysis on Didi data set. There are more and more universities have provided the big data analysis courses with the rapid development and wide application of big data analysis technology. The theoretical knowledge of big data analysis is professional and hard to understand. That may reduce students' interest in learning and learning motivation. And the practice teaching plays an important role between theory learning and application. This paper first introduces the theoretical teaching part of the course, and the theoretical methods involved in the course. Then the practice teaching content of Didi data analysis case was briefly described. And the study selects the related evaluation index to evaluate the teaching effect through questionnaire survey and verify the effectiveness of teaching method. The results show that 78% of students think that practical teaching can greatly improve students' interest in learning, 89% of students think that practical teaching can help them learn theoretical knowledge, 89% of students have basically mastered the method of big data analysis technology introduced in the course, 90% of students think that the teaching method proposed in this paper can greatly improve students' practical ability. The teaching mode is effective, which can improve the learning effect and practical ability of students in data analysis, so as to improve the teaching effect.