The paper presents empirical study of the level of organizational acculturation and the frequency of use of coping strategies in Bulgarian sample. The relationship between them and their dependence on socio-demographic factors were also examined. The aim of the research conducted was to verify the hypotheses that certain socio-demographic factors had a statistically significant impact on the phenomena studied, and that the use of controloriented coping strategies was related to higher levels of acculturation in organization.The results obtained when applying analysis of variance indicated statistically significant differences in the level of acculturation and the frequency of use of coping strategies depending on part of the socio-demographic factors observed, confirming partially the first hypothesis formulated.The second hypothesis was fully confirmed. The findings of correlation analysis indicated that high levels of acculturation in organization correlated statistically significantly with the coping strategies of Increasing efforts, Confidence in success, Change of situation and Time management, all of which are part of the control-oriented coping.