Aim:To study the outcome of microlaryngeal surgery for vocal fold polyp on quality of voice with voice handicap index-10 (VHI-10).Objective: Microlaryngeal surgery for vocal fold polyp will improve the quality of voice. Materials and methods:This is a nonrandomized prospective study with a quasi-experimental design. A total of 36 patients presenting with vocal cord polyp and who underwent a microlaryngeal surgery for the same from March 2016 to August 2016 were included in the study. All the patients were given a self-reporting questionnaire consisting of 10 questions -VHI-10 -and asked to score it. The same questionnaire was given 6 weeks postmicrolaryngeal surgery to these patients and both scores were compared. Results:The mean age of the study population was 44.67 ± 0.34 with the maximum number of patients in the age group 31 to 50. Out of the 36 patients, 27 were males and 9 females. A total of 22 (61%) patients had right-sided polyp and 14 (39%) had left-sided polyp. The majority of the patients were voice professionals, with the maximum number being that of teachers. The mean preoperative and postoperative VHI-10 was 30.36 ± 6.42 and 1.11 ± 1.76 respectively. The reduction in preoperative and postoperative scores gave a p-value of <0.05 at a confidence interval of 95%.