C-Aryl glycoside is a class of structural motifs with important medicinal value. Herein, a remote CÀ H glycosylation strategy enabled by Ruthenium(II)-catalyzed with mostly α-stereoselectivity is described. This approach exhibits great functional group compatibility with various glycosides and arylamides. A series of experiments provided strong evidence for the free radical mechanism and reversible CÀ H activation process, and a possible mechanism was proposed.