A visible-light-induced and iron-catalyzed methylation of arylacrylamides by dimethyl sulphoxide (DMSO) is achieved, leading to 3-ethyl-3-methyl indolin-2-ones in high yields. This reaction tolerates a series of functional groups, such as methoxy, trifluoromethyl, cyano, nitro, acetyl and ethyloxy carbonyl groups. The visible-light promoted radical methylation and arylation of the alkenyl group are involved in this reaction.

No abstract

We herein describle an efficient Cu(I)-catalyzed direct alkoxylation of N-(8-quinolinyl)benzamide with alcohols under air that afforded a number of alkyl aryl ethers in high regioselectivity and good isolated yields. Results and DiscussionRecent studies on the C(sp 2 )À H oxidation of N- (quinolin-8-yl) benzamide reaction reveal that in most cases CÀ H oxidation of arenes requires Ag 2 CO 3 oxidant and alcohol serving as both solvent and reagent. [13,14] The exploration of this alkoxylation was carried out using N-(quinolin-8-yl)benzamide (1 a) and[a] Y. . The scope of alcohols. [a] Scheme 4. Free-radical trapping experiment.Scheme 5. Intermolecular competition experiment. Scheme 6. Removal of 8-amino quinoline unit from 3 a.

To evaluate the safety conditions and deformation characteristics of the cemented tailings backfill (CTB) mining disturbed area near shafts of Taohuazui Gold Mine in China, an analytic hierarchy process-fuzzy comprehensive evaluation (AHP-FCE) model for disturbance degree and safety evaluation of backfill mining was established, the historical and current backfill mining processes were simulated based on 3DEC. The theoretical analysis results were verified by field monitoring during the industrial test. The results show that: (1) More than 80% of historical backfill stopes have a weak disturbance (level II) to the shafts, the distance between stope and shafts (C 1) and the blasting method (C 3) have the most significant influence on the evaluation results. (2) The numerical simulation results validate the rationality of the AHP-FCE model and its evaluation results, and the shafts are in a microdisturbance deformation state of 1-3 mm, which does not exceed the allowable value. (3) The theoretical analysis results are consistent with the field monitoring results, and the disturbance degree and its variation trends induced by the CTB mining are gentle. At present, the overall safety and stability of the shafts and its adjacent areas are good.