There are kinds of animal diseases and a smaller number of experts in the corresponding field of disease diagnosis expert. So animal husbandry units are unable to make a rapid and accurate diagnosis for animal diseases generally. To solve this problem, the paper is proposed a model of animal disease diagnosis expert system based on HSMC-SVM. In theory, it confirms that HSMC-SVM is feasible in applying of animal diseases diagnosis expert system. Numerical experiments verify HSMC-SVM has higher accuracy and better generalization ability in the diagnosis of animal diseases.