This study presents different land saving and loss reducing schemes. Comprehensively compare the economic benefits of the schemes. It is shown that the optimal scheme can recover tons of coal resources on the south slope, creating significant economic benefits. Numerical simulation was utilized to analyze the changes of slope stability, deformation, and shear strain increment in the process of land saving and loss reducing. Results found that the slope stability decreases rapidly, and the toe of the slope has to be internally discharged in time to compress the slope. Timely follow-up of in-slope rows can improve slope stability. The position of the slope shear exit changes with the increase of the distance of the inner row, and its stability increases gradually. When the distance of the lower inner row exceeds 120 m, the increase of the internal row distance has little influence on the slope stability. When the inner distance exceeds 60 m in the process of internal dumping of upper platform, the position of potential sliding plane gradually changes from the lower dump to the upper and lower dump with the increase of inner dumping distance. It shows that the stability of the dump will be damaged if the upper dump continues to be discharged. Therefore, the distance between the upper and lower dump sites is more important than 60 m. The stability of the south slope is good in the process of mining and internal drainage, and the overall stability of the south slope is controllable, based on slope radar monitoring.

Adenovirus vector vaccines have been the mainstream research direction of CSF vaccines, due to the replication deficiency of adenovirus vectors, achieving double effects with the safety of inactivated vaccines and the efficacy of live vaccines. Therefore, the E0 and E2 genes were expressed by an adenovirus vector, a recombinant adenovirus E0-E2 (rAd-E0-E2) vaccine was constructed, and the minimum immunization dose and immune duration period were determined in this study. Forty healthy piglets were randomly divided into 8 groups (n = 5). Groups 1 ~ 5 were used to determine the minimum immunization dose, and 5 groups were inoculated with rAd-E0-E2 at different immune doses. Serum was collected at 7 d and 14 d after immunization to detect CSFV antibodies by ELISA, and piglets were challenged at 7 d post immunization. Groups 6 ~ 8 were immunized with 1 dose of rAd-E0-E2, the CSFV live attenuated vaccine C strain and saline to identify the immune duration period. Serum was collected at different time points after immunization, CSFV antibodies were detected by ELISA, and piglets were challenged at 8 months post immunization. Meanwhile, temperature, clinical symptoms and pathology were observed. The results of groups 1 ~ 5 showed that 1 piglet was protected after challenge, and 4 piglets exhibited high fever retention, typical CSFV symptoms and tissue lesions in the 1/50 dose group, whereas no clinical symptoms were observed in the 1/10 dose, 1/5 dose or 1 dose groups with 5/5 protection after challenge. The minimum dose was determined as 1/10 dose. The results of groups 6 ~ 8 showed that all piglets survived after challenge, but the antibody level of the rAd-E0-E2 strain was higher than that of the C strain at 8 months post immunization, and all piglets in the negative group developed the disease process after challenge. Overall, the minimum immunization dose of rAd-E0-E2 was 1/10 dose (3.16 × 106.0 IFU) and the minimum immune dose was determined to be 1 dose (3.16 × 107.0 IFU) to achieve the expected effects. The immune duration period of piglets immunized with 1 dose of rAd-E0-E2 was at least 8 months.