The current study presents a rhythmic music program to acquire some motor skills for children with Down syndrome. The research sample was taken from one of the specialized Down syndrome learning centers for children, and the sample was taken in a random manner. The sample of children consisted of 20 boys and girls and divided into experimental and control groups. The researcher also prepared a list of the appropriate motor skills for these children (walking, running, jumping, throwing), in addition to the motor skills scale to determine the effectiveness of the proposed program. The results were statistically analyzed using the analysis of covariance, where pre-test serving as a covariate. The results indicated an improvement in the performance of all motor activities under study for the children of the experimental group compared to the control group, and this confirms the extent of the positive impact of the musical rhythmic program for these children, which affects the children positively in the performance of their motor.