An intense fishing activity focused to the capture of shrimp and demersal fishes is developed in the Gulf of Tehuantepec (Mexico). As part of the shrimp trawl fishing the capture of the Lolliguncula panamensis is very abundant. Assess the distribution, abundance, size structure and sexual proportion of the Panama brief squid, in the gulf of Tehuantepec, México. The squids specimens were collected through bycatch shrimp trawlers during November and December 2017, and February (fishing season), May, July and August 2018 (closed fishing season); from five fishing open ocean trips (156 fishing sets). A total of 746 females (21 to 110 mm Mantle length, LM) and 76 males (21 to 93 mm LM) were caught, with the highest abundance (94.5%) between 20 and 30 m deep. Sexual proportion was predominated by females (1M:7H χ2 = 248.81, p < 0.05), whereas size-weight relationship differences were significant (K-S, p < 0.05). The abundant capture of L. panamensis in the Gulf of Tehuantepec, mainly during the fishing shrimp season (rainy season), suggests the importance of the Pacific brief squid as a potential exploitable resource as well as an alternative for fishermen during the fishing closure of resources like shrimp and sharks. Likewise, represents a complementary source of proteins for local populations.