Introduction Low cardiac output states such as left heart failure are characterized by preserved oxygen extraction ratio, which is in contrast to severe sepsis. Near infrared spectroscopy (NIRS) allows noninvasive estimation of skeletal muscle tissue oxygenation (StO 2 ). The aim of the study was to determine the relationship between StO 2 and mixed venous oxygen saturation (SvO 2 ) in patients with severe left heart failure with or without additional severe sepsis or septic shock.
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