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A nonthermal process, high hydrostatic pressure (HHP), was used as a new extraction technique to obtain salidroside from PRACTICAL APPLICATIONSRhodiola is prevalently used as a safe and effective antifatigue drug and as an adaptogen around the world. But the common extraction methods used to yield commercial products are still traditional ones, which could easily lead some thermosensitive ingredients to lose their biologic activities. The nonthermal extraction method is the key point of the realization of herb modernization. The high hydrostatic pressure (HHP) technique can be operated at room temperature and can shorten processing time. The extract produced by the method has proved to be of higher extraction yield than traditional varieties. In addition, the HHP technique only consumes electric energy without exhaust emission, which is an environment-friendly method. In the future, we will cooperate with those far-seeing companies to achieve its industrialization. The