Dialysis disequilibrium syndrome (DDS) is a morbid but rare complication of dialysis. Feared sequalae of this diagnosis are brain herniation and death. This report presents a patient who was diagnosed with DDS with subsequent tonsillar herniation shown on imaging with complete resolution of clinical signs and symptoms, as well as imaging findings of herniation after prompt initiation of intravenous mannitol. This is the first known case of reversal and survival of DDS-induced tonsillar herniation using mannitol.

Sixty cases of trichomonal vaginitis were randomly allocated to treatment with tinidazole or metronidazole, both administered as a 2 g single dose. One patient on tinidazole did not complete her follow-up. Parasitological cure was obtained in all patients in both the treatment groups. A satisfactory clinical response was obtained in all 29 patients on tinidazole, and in 27 out of 30 (90%) on metronidazole. Complete relief of sumptoms was obtained in 62% (18/29) and 13% (4/30) of patients ontinidazole and metronidazole, respectively (p less than 0.01). Ten patients on tinidazole and 24 on metronidazole manifested side-effects. The frequency and severity of side-effects were much more in the metronidazole group (p less than 0.01). Tinidazole has distinct advantages over metronidazole in the one-dose treatment of trichomonal vaginitis.

Plication and resection are surgical procedures commonly used for the treatment of strabismus. Further studies are needed to understand the postoperative effects of plication on muscle tissue. This case report examines a pathological section of a plicated medial rectus muscle, revealing myocyte injury and replacement with fibroconnective tissue. [J Pediatr Ophthalmol Strabismus. 2018;55:e20-e21.].

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