Cognitive radio network (CRN) and non-orthogonal multiple-access (NOMA) is a significant system in the 5G wireless communication system. However, the system is an exceptional way for the cognitive users to secure a communication from the interferences in multiple-input multiple-output (MIMO)-NOMA-based cognitive radio network. In this article, a new beamforming technique is proposed to secure an information exchange within the same cells and neighboring cells from all intervened users. The interference is caused by an imperfect spectrum sensing of the secondary users (SUs). The SUs are intended to access the primary channels. At the same time, the primary user also returns to the channel before the SUs access ends. This similar way of accessing the primary channel will cause interference between the users. Thus, we predicted that the impact of interferences would be greatly reduced by the proposed technique, and that the proposed technique would maximize the entire secrecy rate in the 5G-based cognitive radio network. The simulation result provides better evidence for the performance of the proposed technique.

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