There have been an increased number of recent reports on orgasm-related sexual dysfunction coincident with selective serotonin reuptake inhibitor (SSRI) treatment. In contrast, it has also been reported that SSRIs improve sexual dysfunction. Low doses of clomipramine and paroxetine, potent 5-hydroxytryptamine reuptake blockers, have been found to retard ejaculation time. We hypothesized that the SSRI fluoxetine might be effective in treating premature ejaculation. In an 8-week open-label clinical study, 11 male patients with premature ejaculation were treated with fluoxetine. After a washout period of 2 weeks, each patient was assigned to receive fluoxetine, 20 mg/day for 2 weeks, and then titrated to 60 mg/day, depending on the patient's tolerability and clinical response. A within-subjects comparison of pre- and posttreatment intravaginal ejaculation latency time revealed a significant improvement. Fluoxetine treatment produced significant improvements in self-visual analogue scale scores for sexual desire, anxiety for rapid ejaculation, and partner's satisfaction with ejaculation and overall sexual function. These data suggest that serotonergic antidepressants may be effective in treating rapid ejaculation in men and underline the need to carry out a double-blind, placebo-controlled trial to confirm these results.
Presently, the demand for IPTV, to satisfy a variety of goals, is exploding. IPTV is coming into the spotlight as a killer application in upcoming IP convergence networks such as triple play which is the delivery of voice, internet, and video service to a subscriber. IPTV utilizes CAS, which controls the subscriber access to content for a profit. Although the current CAS scheme provides access control via subscriber authentication, there is no authentication scheme for the content transmitted from service providers. Thus, there is a vulnerability of security, through which an adversary can forge content between the service provider and subscribers and distribute malicious content to subscribers. In this paper, based on a hash tree scheme, we proposed efficient and strong source authentication protocols which remove the vulnerability of the current IPTV system. We also evaluate our protocol from a view of IPTV requirements.
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