Ordinary lipomas are the most common neoplasm ofmesenchymal origin. About 13% ofthem arise in the head and neck region. especially in the posterior neck. More than 80% of lipomas are ordinary lipoma, and histologically they are composed of mature fat.CT scan provides a definite diagnosis of lipoma in virtually all cases due to their characteristic finding ' a homogenous. well.defined low.atte nuation mass that usually m easures between -65 to -125 HU The authors reviewed the clinical and CT characteristics of 14 cases of lipoma in the neck.The results were as follows:1. A palpable nec k m ass was the most common symptom having a variable duration (months to years). 2. The age distribution of the patients was from 29 to 64 years, and the 6th decade was the most commonly af.
Purpose
To evaluate and compare the diagnostic outcomes of ultrasonography (US)-guided fine needle aspiration (FNA) and core needle biopsy (CNB) performed on the same thyroid nodule using a surgical specimen for direct comparison.
Materials and Methods
We included 89 thyroid nodules from 88 patients from February 2015 to January 2016. The inclusion criterion was thyroid nodules measuring ≥ 20 mm (mean size: 40.0 ± 15.3 mm). Immediately after surgical resection, FNA and subsequent CNB were performed on the surgical specimen under US guidance. FNA and CNB cytopathologic results on the specimen were compared with the surgical diagnosis.
Results
Among the 89 nodules, 30 were malignant and 59 were benign. Significantly higher inconclusive rates were seen in FNA for malignant than benign nodules (80.0% vs. 39.0%,
p
< 0.001). For CNB, conclusive and inconclusive rates did not differ between benign and malignant nodules (
p
= 0.796). Higher inconclusive rates were seen for FNA among cancers regardless of US features, and in the subgroup of size ≥ 40 mm (62.5% vs. 22.9%,
p
= 0.028). Eleven cancers were diagnosed with CNB (36.7%, 11/30), while none was diagnosed using FNA.
Conclusion
In this experimental study using surgical specimens, CNB showed a potential to provide improved diagnostic sensitivity for thyroid cancer, especially when a conclusive diagnosis is limited with FNA.
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