Although injury rates may have been underestimated owing to data limitations, we are confident that South Korea's rate is higher than those seen in other countries or occupations.
Objectives: We focused on the relationship between symptoms of depression and emotional labor to investigate the mental health status of workers. Methods: In this cross-sectional study, a total of 2,346 workers among bankers were our study subjects. A self-administered questionnaire was used to assess the socio-demographics, job characteristics, emotional labor and, the Center for Epidemiologic Studies-Depression scale (CES-D). We used multiple logistic regression analysis to estimate the relationship between emotional labor and the symptoms of depression. Results: The prevalence of symptoms of depression among the survey subjects was 20.6%. After adjusting for confounding factors, emotional effort (OR: 1.7, 95% CI=1.28~2.31) and, emotional disharmony (OR: 4.5, 95% CI=3.13~6.44) in men and emotional effort (OR: 1.9, 95% CI=1.33~2.75), emotional disharmony (OR: 6.1, 95% CI=4.12~9.09) in women showed a statistically significant association with symptoms of depression. Conclusions: These results suggest that emotional disharmony and emotional effort are related to symptoms of depression. Managing emotional disharmony is important in managing symptoms of depression.
Deferoxamine (DFX), a potent iron-chelating agent, reduces brain edema and neuronal cell injury that develop due to the hemolysis cascade. Statins have neuroprotective effects via anti-inflammatory action and increment of cerebral blood flow after intracerebral hemorrhage (ICH). The purpose of this study was to identify the effects of combined DFX and statins treatment in an experimental ICH rat model. The treatments were: intraperitoneal (i.p.) injection of DFX (group I), combined treatment of i.p. DFX and oral statins (group II), statins only (group III) and treatment with vehicle (group IV). Induction of ICH was performed with injection of bacterial collagenase type IV into the left striatum. After removal of the brain, hematoma volume, water content and brain atrophy were measured. Immunohistochemistry in the perihematomal region was performed for identification of microglial infiltration, astrocyte expression and apoptotic cell presence. Statistical analysis was performed using the non-parametric Kruskal-Wallis test and significance was evaluated when the p value was less than 0.05. According to behavioral tests, significant differences among treatment groups were noted 4 weeks after ICH induction (p < 0.05). However, there were no significant differences among treatment groups in hematoma volume, brain water content or brain atrophy. In the perihematomal area, the activated microglial cells were reduced in the combined treatment group. Among the four groups, a significant difference in immunohistochemical staining was identified (p < 0.05). These results suggest that combined treatment with DFX and statins improves neurologic outcomes after ICH through reduction of microglial infiltration, apoptosis, inflammation and brain edema.
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