Purpose: The advancement of technologies and their adoption affects the socio-economic growth of nations. This research is focused on how this innovation adoption path is linked to economic growth of nations since the previous IT revolution has been combined with existing industries and adding values in terms of applying intelligence through adopting digital technologies. Approach/Design/Methodology: There are two different approaches-process approach and factor approach-in innovation adoption research. Innovation diffusion research, which is one of the process approaches, is related to adoption, diffusion, and impact theories, but there are limitations in explaining the perspective of a nation other than individual and organization on the basis of previous literatures. Therefore, we build the integrative model to verify innovative growth path of nations by applying Diffusion of Innovation Theory (DoI) and Technology (T)-Organization (O)-Environment (E) framework, which can explain factors of affecting innovation. We evaluate eight hypotheses with data collected from 137 to 212 nations using international information index by credible organizations: World Economic Forum (WEF), World Bank, United Nations (UN), and International Communications Union (ITU), based on the integrative model we proposed. The path analysis using Structural Equation Modeling (SEM) is performed, and the result shows that the path from technological innovation capabilities (T), human capital (O), and environment (E) is related directly to economic impact, except for the path from human capital to value chain breadth directly and indirectly. The indirect path through Information and Communication Technology (ICT) access, use, and value chain helps to understand the full impact of digital innovation. Practical implications: By verifying this relationship, we expect to give suggestions in policy perspective and in building strategy towards innovative growth of countries. Our results show that technological innovation capabilities take time to show impact in terms of economic growth than the other factors, which are human capital, and political and regulatory environment of country. The nurture of human capital directly affects to the economic growth of nations relative to other T and E factors. The political and regulatory environment support stable ICT usage, which gives impact to the economic growth of nations. communication technologies makes organizations to actively expand their business globally in terms of production network. The development of Information and Technology, and digitalization [1] is at the center of this global production network. The advancement of ICT has improved national economies, social progress, and industrial development [2], which is why the phenomenon driven by ICT is called the Third Industrial Revolution. Based on the network connectivity, interactive organizations and information exchanging are all promising across the border; therefore, the adoption of digital technologies based on ICT is considered to be an...

The Cav1.2 Ca2+ channel is essential for cardiac and smooth muscle contractility and many physiological functions. We mutated single, double, and quadruple sites of the four potential Asn (N)-glycosylation sites in the rabbit Cav1.2 into Gln (Q) to explore the effects of Nglycosylation. When a single mutant (N124Q, N299Q, N1359Q, or N1410Q) or Cav1.2/WT was expressed in Xenopus oocytes, the biophysical properties of single mutants were not significantly different from Cav1.2/WT. In comparison, the double mutant N124,299Q showed a positive shift in voltage-dependent gating. Furthermore, the quadruple mutant (QM; N124,299,1359,1410Q) showed a positive shift in voltage-dependent gating as well as a reduction of current. We tagged EGFP to the QM, double mutants, and Cav1.2/WT to chase the mechanisms underlying the reduced currents of QM. The surface fluorescence intensity of QM was weaker than that of Cav1.2/WT, suggesting that the reduced current of QM arises from its lower surface expression than Cav1.2/WT. Tunicamycin treatment of oocytes expressing Cav1.2/WT mimicked the effects of the quadruple mutations. These findings suggest that Nglycosylation contributes to the surface expression and voltage-dependent gating of Cav1.2.

Objectives: This study examined whether homeownership is associated with life satisfaction and depressive symptoms among older adults aged 65 or over and whether these associations differ by gender. This study further distinguished mortgagors from owner-occupiers. Methods: Using six waves of the Korean Longitudinal Study of Ageing ( N = 3540), we used generalized estimating equations as well as random- and fixed-effects regression analyses. Results: Gender-stratified fixed-effects models showed that the associations between homeownership and psychological resources are largely driven by men. Owner-occupiers are more satisfied with life and report fewer depressive symptoms than renters. By contrast, although mortgagors are more satisfied with life than renters, they have depressive symptoms similar to those of renters. These patterns are more pronounced among men than women. Discussion: Our findings lend support to policies that promote affordable homeownership as a way to reduce social inequalities in psychological well-being and health, especially among older men.

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요 약 본 연구는 호텔기업의 종사원을 연구대상으로 하여, 소셜네트워크서비스(SNS) 품질의 중요도를 분석함으로 써 향후 호텔기업 소셜네트워크서비스의 효율성 증대에 기여하고자 함을 목적으로 한다. 선행연구에 의거하여 호텔기 업의 SNS 품질요인을 소셜네트워크서비스 정보품질, 시스템품질, 서비스품질, 인터페이스품질, 감성품질 등으로 분류 하였다. 계층적 의사결정방법(AHP)을 이용한 실증분석결과에 의하면, 중요도 측정결과로서 감성품질영역이 상대적으 로 가장 주요한 요인으로 도출되었으며, 인터페이스품질, 시스템품질, 정보품질, 서비스품질 등의 순으로 중요도가 높 은 것으로 나타났다.Abstract This study is focused on analyzing the quality importance of hotel SNS(social network service). And by reviewing precedent papers and references regarding concept and quality factors about SNS in hotel industry, it drew proper criteria to select priorities and evaluate hotel SNS quality using AHP. The important factors based upon related theories are suggested in this paper such as information quality, system quality, service quality, interface quality and emotional quality. The survey for empirical study was executed with hotel employees and total 149 questionnaires were used for this study. We used AHP for statistical analysis, As the results, the most important factor is emotional quality factor and the next is interface quality factor.