Background: Skin diseases that cause chronic pruritus can have negative effects on a patient's quality of life.Objective: We evaluated the associations between chronic pruritus and psychological conditions including insomnia and depression.Methods: This study included responses from 91 participants with chronic pruritus (response rate: 74.6%). A survey including questionnaires regarding data on demographic characteristics, intensity of pruritus using the visual analog scale (VAS) and the 4-item itch questionnaire, and the degrees of insomnia and depression measured by the Insomnia Severity Index and Beck Depression Inventory, respectively.Results: Patients with symptoms of insomnia or depression had significantly more intense pruritus than patients without psychological symptoms (insomnia, VAS median [interquartile