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Background: Peroral endoscopic myotomy has recently been developed and performed on patients with good results. Aims: To evaluate the technical feasibility of peroral endoscopic full-thickness and partial thickness myotomy in a porcine model. Material and methods: Eighteen criollo pigs were randomly assigned to 2 groups: group A (partial-thickness myotomy) and group B (full-thickness myotomy). The mucosal defect proximal to the myotomy site was left open. On the seventh postoperative day the pig was euthanized and follow-up surgical exploration was performed. The duration of each procedure, postoperative progression of the animal, complications, and anatomopathologic findings were registered. ଝ Please cite this article as: Quiroz-Guadarrama CD, Rojano-Rodríguez M, Herrera-Esquivel, JJ, et al. Miotomía endoscópica por vía oral de espesor total y parcial. Estudio de factibilidad en un modelo animal. Revista de Gastroenterología de México. 2013;78:225---230.

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