An abscess of the round ligament of the liver in children, as a result of an inflammatory process, often leading to necrosis, is an extremely rare occurrence. Formations in the round ligament of the liver must be differentiated from liver tumors, which can be diagnosed using instrumental research methods. In the available literature on the abscess of the round ligament of the liver, the authors speak about the preference for complete excision of the ligament. However, analyzing the experience (5 clinical examples are given) of the surgical clinic of the N. F. Filatov Children’s City Clinical Hospital (Moscow, Russia), the most preferable and safe are puncture and drainage of the abscess cavity from the anterior abdominal wall under visual control of manipulation using a laparoscope.