Rabies is a zoonotic disease that can attack the central nervous system and can be fatal because it can cause death. Rabies is caused by an RNA virus of the genus Lyssavirus in the family Rhabdoviridae and can be transmitted to humans through contact with infected animals, particularly bites and scratches. Most cases (98%) were caused by dog   bites and the rest by other animals such as monkeys and cats. This disease has a very poor prognosis, but can be prevented by vaccination. Rabies virus is a neurotrophic virus that can infect humans and cause fatal encephalitis. The purpose of this paper is to provide information on rabies cases, prevention, early symptoms to watch out for, and emergency management. A 45-year-old man has clinical encephalitis with suspected viral EC with suspected rabies dd/non-specific viral dd bacterial. Patients complain of not being able to swallow and afraid of water, restlessness, hypersalivation, patients are sensitive to sound, shortness of breath, difficulty swallowing, fear of wind, patients want to bite and hydrophobia, aerophobia and hypersalivation. Therapy in cases of rabies is to provide supportive care and isolation treatment. The prognosis for rabies patients is generally poor, because mortality can reach 100% after the rabies virus reaches the central nervous system, death from respiratory/cardiac arrest most often occurs within 2-3 days after the onset of rabies symptoms. After being bitten by an animal suspected of being rabid, cleaning the wound, administering VAR and SAR is an effective preventive measure against the transmission of the rabies virus.

Stroke is a real cause of death and disability worldwide. Stroke is the second leading cause of death in the world and the leading cause of severe long-term disability. Between 1990 and 2019, the incidence of stroke increased by 70%. In Indonesia, stroke occupies the first position in the group of degenerative diseases after heart disease and malignancy which are the deadliest diseases in Indonesia. Stroke is one of the most expensive diseases, costing health services Rp 2.56 trillion in 2018. Stroke is a functional brain disorder that appears suddenly with focal and global clinical signs and symptoms, lasts more than 24 hours, and can be fatal. in the absence of any other apparent cause other than vascular. In UPTD RSU Negara, the incidence of stroke increases by the end of 2021 is the case of inpatient care in UPTD RSU Negara as 550 people and outpatient in UPTD RSU Negara as many as 1550 people. The purpose of this study was to determine the knowledge and attitude of the family on the ability of early detection of stroke. This research method using descriptive method of analysis with crossectional approach by using questioner and then processed data using chi squere test. The sample in this research is 40 people. The result of the statistical test in obtaining the result between the knowledge of the family on the ability of early detection in stroke patient P Value = 0,011 (P> α), it can be concluded there is correlation of knowledge to the ability of early detection with value (P = 0.011 OR = 3,927). Based on statistical test result between family attitudes toward the ability of early detection (sign and symptom) got result P value = 0,186 (P <α) this show that there is no relation between family attitude with ability of early detection in stroke patient in UPTD RSU Negara tahun 2022. Suggestions in this study can be used as input for the hospital in order to improve health service and able to increase promotive effort by giving education of stroke attack to the family.

Hypokalemic periodic paralysis is characterized by muscle weakness or flaccid paralysis followed by low potassium levels (less than 3.5 mmol/L) during the attack. Proper initial management and patient education are mandatory for health workers to manage this case. This study was a descriptive study with a case report approach. This case report includes patients over 18 years receiving health care at the Negara General Hospital and having accessible medical record data. Data collection was carried out consecutively. A case from a 22-year-old man with complaints of weakness in both legs. The examination found lower extremity motor strength 2/2, normal physiological reflexes without pathological reflexes, and a laboratory potassium level of 2.5 mmol/L laboratory results. The patient was then given hypokalemia treatment with KCl intravenously. The patient, in this case, had no clinical condition contraindicated to give potassium. Within 24 hours after potassium administration, the patient showed a significant improvement. Hence, our therapy, in this case, was in line with the theory with a good clinical outcome. Symptomatic therapy in hypokalemic periodic paralysis provides a good clinical outcome. There were no complications or clinical emergencies during treatment.