Management information system collects and processes data (information) and provides it to managers at all levels who use it for decision making, planning, program implementation, and control. In addition to the global studies of management information system, this paper will analyze similar cases in Albanian enterprises. Albanian enterprises strongly need management information systems and the facilities that they bring to their management ensuring a better functioning and higher performance of different enterprise processes. In this paper was taken the case study of the Microsoft Dynamics NAV system, the implementation in “Infosoft Systems” enterprise in Albania and the impact of NAV system in some of the enterprise departments. Implementation phase of management information system is one of the most important stages which starts with the organization of the information systems management department and ends with the procurement of the relevant software. To get more information we used a questionnaire which was designed and sent to some enterprises in Albania. The purpose of this questionnaire was to learn how many of them use management information systems, what type of information system they use and the advantages or benefits that the implementation of information systems brings to enterprises in Albania. As a conclusion, management information systems have contributed to enterprises to put in place better functionality, which leads to increased enterprise performance, increased profits, simplified work processes in different departments.