The performed investigation has shown that there is an increase of the content of CD4+ lymphocytes and an increased expression of γ-interferon in the skin of patients with atopic dermatitis comparing to healthy volunteers. Therapy with the use of UFA-1 produced more marked levels of γ-interferon positive cells in the skin (р = 0.004) in patients with clinical recovery compared to subjects with an achieved improvement, as well as a substantial reduction of the Т-helpers level within the effected skin areas (р = 0.009).
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