This paper deals with an analytical model of the virtual air gap function in order to define design rules when this technique is used inside complex devices. The establishment of those design rules constitutes the main originality of the developments presented in the paper, which are about a single phase magnetic core. It is based on the definition of a nonlinear reluctance network that takes simultaneously into account the effects of DC and AC magnetic flux components in the disturbed area that contains the virtual air gap. The results are validated using a finite element analysis and experimentally.

Rationale, aims and objectives :Over the past decades, thrombophilia testing in patients with venous thrombo-embolism (VTE) has increased tremendously. However, the role of inherited thrombophilia (IT) in prediction the risk of recurrence remains controversial. Consequently, it is still unclear whether thrombophilia testing influences decisions regarding duration of anticoagulation in clinical practices. The aim of this study was to evaluate the impact if IT on VTE treatment decisions and on predicting the risk of recurrence. Methods : A retrospective longitudinal study (January 2011-Decembre 2016) including 190 patients with confirmed VTE referred from internal medicine department for inherited thrombophilia screening was carried out. Results : The mean age patients was 40.2 years and the sex ratio (M/F) was 0.78. IT was confirmed in 27.5% of patients. A long term anticoagulation was decided in 51.6% of patients with IT. There was no significant difference in the duration of anticoagulation between patients with or without IT. VTE recurrence was recorded in 26 (13.7 %) patients. The 24 years cumulative incidence of recurrence was 9% in patients with IT and 14% in those without. IT was not associated with increased risk of recurrence after treatment withdrawal (Hazard ratio=1.31 IC(0.47-3.63); p=0.6). Conclusion : In clinical practice, IT did not influence anticoagulation duration and was not associated with a higher VTE risk of recurrence. It seems to be less relevant for decision making than presumed.

Erdheim-Chester disease is a rare multisystemic disease. A 50-year-old woman, presented with a recurrent pain and swelling of the left knee. Bone scintigraphy showed increased tracer uptake of peripheral skeleton. The computed tomography showed tissular infiltration in the retroperitoneum, around the vessels.Immunohistochemistry showed CD68 (+) and CD1a (−).

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