Every other day supplementation with 250 mg vitamin C for 12 weeks increases serum vitamin C, decreases MDA levels, and improves lipid profiles in hemodialysis patients.
A Ab bs st tr ra ac ct t Many factors such as aging, changes in blood electrolytes levels, and possibly family history are involved in senile cataract formation. Changes in serum electrolytes levels can induce changes in aqueous electrolytes levels and effect on lens metabolism and probably cataract formation. In this paper, we study serum level of Na + and K + in senile cataract patients and normal individuals.
Objective: Several studies on cataract have suggested that antioxidant micronutrients such as α-tocopherol, retinol and ascorbic acid may help to protect against cataractogenesis. Our objective was to determine the serum concentration of these antioxidant vitamins in subjects with cataract to see if there is any correlation between the levels of essential vitamins and the development of cataract. Methods: The study was performed on a total of 88 patients and healthy controls who were given physical examinations that included a complete eye examination. Ascorbic acid was measured in serum with UV/Vis spectrophotometry, and fat-soluble vitamins were measured in serum by high-performance liquid chromatography according to previously published methods. Results: The mean serum concentration of α-tocopherol in patients (9.16 ± 2.53.µg/ml) with cataract was lower than in the control group (p < 0.001). Patients had a moderately lower ascorbic acid concentration than the control group, which was not statistically significant. The subjects’ serum retinol levels were similar to control group levels and not statistically significant. Conclusion: While this is a small-scale case study it can nonetheless be viewed as presenting support to help narrow the possibility that antioxidative agents may play a role in delaying cataract formation.
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