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Data of experimental and clinical studies concerning fibrin adhesives’ use for theprotection of anastomoses of the gastrointestinal tract are submitted in the article.Definite data have not been obtained.Objective. The purpose of this study was to review literature on the protection ofanastomoses of the digestive system by fibrin adhesives. The study was conductedaccording to the Internet data.Conclusion. The given data testify that anastomoses strengthening with fibrin adhesivescan be effective in bariatric surgery. The majority investigations, preferably on rats,are an experimental research. It is premature to give recommendations concerningapplication of fibrin adhesives to strengthen other types of anastomoses. Fibrin adhesives’investigations in strengthening gastrointestinal tract anastomoses represent a perspectivedirection of up-to-date surgery. Significant achievements should to be expected.

The aim of the work is to determine the dynamics of the incidence of malignant neoplasms of the abdominal cavity in the Bukovina region and possible determinants. Material and methods. The study was performed on the basis of RMNE "Chernivtsi Regional Clinical Oncology Center" and Clinic of Oncology of Bukovinian State Medical University and covers observation materials during 2015-2019 and statistical reporting on 102,247 cases of tumors of various localizations. The indicators were calculated using Access and Excel software packages based on the Microsoft Office environment. The results. The total number of malignant neoplasms of different localizations is relatively stable throughout the study period and ranged from 19903 to 21259 cases per year (average 20449.4±508.2 registered during the year). Neoplasms of the abdominal cavity are about the third of the total number of tumors of different localization with a certain tendency to grow. The distribution of patients with neoplasms of the abdominal cavity by stages of development is relatively uniform, despite significant variations in different localizations of tumors. Conclusions. A significant part of tumors of the abdominal cavity is diagnosed in the late (III-IV) stages of the pathological process, which leads to a decrease in the effectiveness of treatment. Significant differences in the clinical and epidemiological characteristics of neoplasms of various abdominal organs have been identified, which requires further study.