I. Reguigne scite author profile

The last step in the biosynthesis of Le^x antigen, the addition of a fucose to precursor polysaccharides, can be catalyzed by different α-3-fucosyltransferases. We localized the gene (FUT4) encoding myeloid α-3-fucosyltransferase by PCR assay using panels of somatic cell and radiation hybrids which retain different rearrangements of chromosome 11. FUT4 was assigned to chromosome band 11q21 between D11S388 and D11S919.

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I. Reguigne

Molecular basis for Lewis alpha(1,3/1,4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees.

Molecular basis for plasma alpha(1,3)-fucosyltransferase gene deficiency (FUT6).

Assignment of 112 Microsatellite Markers to 23 Chromosome 11 Subregions Delineated by Somatic Hybrids: Comparison with the Genetic Map

Molecular genetics of α-L-fucosyltransferase genes (H, Se, Le, FUT4, FUT5 and FUT6)

The gene encoding myeloid α-3-fucosyltransferase (FUT4) is located between D11S388 and D11S919 on 11q21

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