Variations in hematocrit and hemoglobin values are constantly checked in patients with chronic kidney disease (CKD) on dialysis in order to monitor the anemia. Anemia and iron deficiency are the most frequent and severe nutritional deficiencies, acting as a cause of morbidity in individuals carrying CKD. The work aimed to monitor the evolution of laboratory parameters of chronic renal patients on dialysis of a clinic in the state of Paraná, Brazil, for twelve months, correlating them with the drug therapy (iron injection and EPO). This is a cross-sectional investigation of quantitative character, whose data were collected from the results of laboratory tests of 108 adult patients. The data showed that at the beginning of the study 86.1% of patients were anemic; the number of patients with serum iron less than 50µg/mL increased 27%, and the number of patients with TSAT<20% increased 129%. The results emphasize the importance of careful evaluation of laboratory values by the health professionals, especially the nephrology clinical team, who deal with patients with CKD through the identification and correction of clinical and laboratory factors that alter the clinical picture of the patient.Keywords: Chronic renal disease. Anemia. Dialysis. RESUMOAs variações nos valores de hematócrito e hemoglobina são constantemente avaliadas em pacientes com doença renal crônica (DRC) em diálise para controlar a anemia. A anemia e deficiência de ferro são mais frequentes e graves deficiências nutricionais, atuando como causa de morbidade em indivíduos portadores de DRC. O trabalho teve como objetivo acompanhar a evolução dos parâmetros laboratoriais de pacientes renais crônicos em diálise de uma clínica no estado do Paraná por doze meses, correlacionandoos com a terapia medicamentosa (injeção de ferro e EPO). Trata-se de uma pesquisa transversal de caráter quantitativo, cujos dados foram coletados dos resultados dos testes laboratoriais de 108 pacientes adultos. Os dados mostraram que, no início do estudo, 86,1% dos pacientes eram anêmicos; o número de pacientes com ferro sérico inferior a 50µg/mL aumentou 27%, e o número de pacientes com TSAT<20% aumentou 129%. Os resultados ressaltam a importância de cuidadosa avaliação dos valores de laboratório
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