The objective of this study was to develop a mucoadhesive buccal patch of Ivabradine hydrochloride using mucoadhesive polymers such as carbopol, poloxamer, and HPMC 15LV. During this study polyvinylpyrrolidone, ethyl cellulose considered as a thickening agent or rate controlling polymer. A total number of five formulations were prepared by a solvent evaporation method. The prepared mucoadhesive patches were evaluated for in-vitro dissolution, drug content, folding endurance, mucoadhesive strength, swelling index, and drug-polymer interaction study. From the present study, it found that the mean thickness of the buccal polymeric patches increased with an increase in the amount of polymer percent. Percent swelling index determined at 2, 4, 6 and 8 hrs increased with time and with an increase in the polymer. The in-vitro study was performed by phosphate buffer PH 6.8 in Franz diffusion cell. During the study, it was also found that an increase in the amount of polymer retarded the release of the drug. Formulation F3 released 100% of the drug in 10 hrs of time. There was no such interaction found between drug and excipients.