The gender peculiarities of metabolic status were studied in patients with acute coronary syndrome who underwent outpatient rehabilitation in the day hospital. It was found that in the overwhelming majority of patients of both sexes there was not only an increase in body mass index values relative to normal values, but also the waist circumference as a sign of abdominal fat tissue deposition. In the group of women the values of these indices were higher than in men. They were much more frequently diagnosed with 1st and 3rd degree obesity as compared to men with higher frequency and severity of abdominal obesity. The study of blood lipid and carbohydrate spectra revealed initially more significant fat metabolism disorders in male patients, but in comparison with female patients after rehabilitation measures more pronounced positive dynamics of blood biochemical indices was observed: decrease of values of low density lipoproteins, atherogenicity index and triglycerides. In carrying out stress testing, men, compared with women, both before and after rehabilitation showed a higher tolerance for physical activity and aerobic reserves of the cardiorespiratory system, which, among other indicators, indicates a higher efficiency of their rehabilitation course.
To assess endothelial function in the newborns born to mothers with preeclampsia and without preeclampsia the scientists assessed the content of nitricoxide and hydrogen sulfide in the umbilical and venous blood of these children. The main group consisted of 80 women with moderate preeclampsia and their80 newborns; the control group included 50 children born to women without preeclampsia. The authors studied the content of nitric oxide by determining the totalnitrates and nitrites (NOx), hydrogen sulfide in mixed cord blood collected within 30 minutes after delivery, and venous blood taken from newborns on the 1-3rd day of life. Umbilical cord blood demonstrated no significant differences in the content of NO xand hydrogen sulfide in newborns of the main and control groups. However, in general, the study of umbilical cord blood revealed a relationship between the concentration of hydrogen sulfide and the possibility of developing intraventricular hemorrhagein a newborn of the main and control groups. In the venous blood there was a significant increase in the content of NOx and hydrogen sulfide in newborns born to mothers with preeclampsia. It may cause vasodilation asa compensatory reaction of the body during the period of postnatal adaptation of the child’s body, aimed at life support.
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