No abstract

The analysis of fatty acid profiles of lipopolysacharid.es has shown that R. solanacearum strains tested may be divided into two groups. The first group is represented by R. solanacearum strains (5712, 7945, 7955 and 8110) the lipids A of which contained hydroxylated fatty acids with long chains: 3-hydroxy tetradecanoic, 2-hydroxyhexadecanoic and 2-hydroxyoctadecanoic. The second group was represented by R. solanacearum strains the lipids A of which contained hydroxylated fatty acids with short chains: 3-hydroxydecanoic, 2-hydroxydodecanoic and 3-hydroxydodecanoic. 3-hydroxytetradecanoic acid was observed in a small amount. A comparative analysis of the fatty acid composition and biological activity gives a possibility to suppose that 3-hydroxytetradecanoic, 2-hydroxyhexadecanoic and 2-hydroxy octadecanoic acids may be responsible for the toxicity and pyrogenicity of the lipopolysaccharides tested.

The synthesis of the benzofuroxanes (IIIa) and (IIIb) is described.

The chlorine atoms of the title compounds (I) and (XIII) are activated by the neighboring and strongly electrophilic trifluorosulfonyl (Tf) and nitro groups and, hence, are easily accessible to substitution by nucleophiles.

Functionalized 2-Carene Derivatives in the Enantioselective Synthesis of Cyclopropane Containing Pyrethroids.-Epoxidation and cyclopropanation of derivatives such as (I), (VI), and (XV) are found to proceed stereoselectively yielding products like (II) , (VII), (XI), and (XVI).In the presence of bases the products undergo 6-membered ring opening to afford cyclopropane derivatives such as (IX), (XIII), and (XIV), which are useful pyrethroid precursors. In contrast, in the presence of acids they undergo exclusively 3-membered ring opening giving molecules like (III)-(V) and (XVII). -(FOKIN, A. A.; BUTOVA, E. D.; KOLOMITSIN, I. V.; GAGAEVA, E. A.; GOGOMAN, I. V.; KORNILOV, A. M.; SOROCHINSKII, A. E.; YURCHENKO, A. G.; KRASUTSKII, P. A.; Zh. Org. Khim. 30 (1994) 5, 669-679; Kievskii politekh. inst., Kiev, Ukraine; RU)