242 patients with discirculatory encephalopathy were examined: 120 of them were the liquidators of the Chernobyl nuclear disaster and 122 patients were without radiation anamnesis. We studied the variants of structural changes of the main brain arteries by ultrasonic scanning. We arrived at a conclusion that that liquidators of the Chernobyl APP had an acute form of main brain arteries’ affection. Radiation effect correlates with the significant hemodynamics stenosis of the internal carotid artery (r = 0,5; р < 0,05).
It has been determined that the formation of paroxysmal brain activity in LCND occurs 3.5 times more frequent (p<0.001) and 15-17 years earlier (p<0.001) than in the control group and mainly during the first 10 years after the exposure to radiation. The history of the exposure to ionizing radiation is associated with the increased risk of the development of convulsive PBA as focal seizures by 5.5 times (p<0.001), interictal epileptiform discharges (IED) in EEG by 3.3 times (p<0.001). Radiation effect on LCND under 30 years old increases (as compared to the control group) the risk of the formation of elevated paroxysmal brain activity by 19 times (p<0.001), convulsive epileptic seizures by 33.3 times (p<0.001), interictal epileptiform discharges in EEG by 12 times (p<0.001), asymptomatic focal epileptoid nidus in EEG by 9.3 times (p<0.001). Stimulating effect of ionizing radiation on the development of PBA related to the age on the date of exposure to radiation was found.
государственный медицинский университет Министерства здравоохранения РФ, ректор-д. м. н., проф. В. М. Брюханов; кафедра внутренних болезней стоматологического и педиатрического факультетов, зав.-д. м. н., проф. А. В. Молчанов; 2 ГБОУ ВПО Красноярский государственный медицинский университет имени проф. В. Ф. Войно-Ясенецкого Министерства здравоохранения РФ, ректор-д. м. н., проф. И. П. Артюхов; кафедра нервных болезней с курсом медицинской реабилитации ПО, зав.-д. м. н., проф. С. В. Прокопенко. v%+< (11+%$."-(?. Определить значимость пароксизмальной активности головного мозга (ПАГМ) в прогрессировании когнитивных расстройств у ликвидаторов последствий аварии на Чернобыльской АЭС. l 2%0(+; (,%2.$;. Проведено нейропсихологическое тестирование и ЭЭГ-обследование 195 мужчин в возрасте от 30 до 65 лет, из них: 105 ликвидаторов и 90 лиц без радиационного анамнеза. p%'3+<2 2;. Наличие интериктальных эпиразрядов на ЭЭГ коррелирует с легкими и умеренными когнитивными нарушениями, ПАГМ с эпиприступами-с умеренными и выраженными когнитивными расстройствами. g *+>7%-(%. У ликвидаторов, проживающих в Алтайском крае, формирование ПАГМ способствует большему нарушению интегративных функций головного мозга. j+>7%";% 1+." : пароксизмальная активность головного мозга, когнитивные нарушения, ликвидаторы последствий аварии на Чернобыльской АЭС.
Results obtained over 20-years of following 536 Chernobyl clean-up workers and 436 control subjects are presented. Dyscirculatory encephalopathy developed more frequently in persons exposed to radiation at age 30 years. As compared with the control group, workers were characterized by early onset of disease, faster progression, stable symptomatology for 5-6 years, and further progression of disease in the form of autonomic dysfunction, psycho-organic syndrome, and epilepsy. Major strokes were also more common in clean-up workers.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.