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Проведен анализ литературных данных по содержанию в растениях рода Teucrium L. (Дубровник) комплекса вторичных метаболитов: эфирного масла, фенольных соединений (флавоноиды, иридоиды), дитерпеноидов, гидроксикоричных кислот. Описан спектр биологической активности этих соединений как в норме, так и при различных патологических состояниях. Необходимость определения основных показателей качества, разработки методик стандартизации сырья указывают на перспективность дальнейшего более глубокого исследования видов Teucrium L., которые могут являться источниками фармацевтических субстанций для получения новых лекарственных средств, обладающих антибактериальным, антимикробным и радиопротекторным действием.

The genus Rhus of the Anacardiaceae family includes about 120–150 species of small trees, bushes, and lianas. The chemical composition of the sumac fluffy Rhus typhina (L.) is almost unknown. Previously, some phenolic compounds (rutin, quercetin, hyperoside, tannin, gallic acid) were identified in the fruits of the plant. To quantify the amount of phenolic compounds in the raw materials studied, a method based on the complexation reaction of phenolic compounds with a phosphomolybdic-tungsten reagent (Folin-Denis reagent) in an alkaline medium was chosen. The optimal conditions for the complexation reaction are selected: the ratio of the solution of gallic acid and Denis-Folin reagent is 0.06 mg / 1.6 ml, respectively. For the quantitative determination of the amount of phenolic compounds for the aqueous extraction of sumac fluffy must be added 1.1 ml of Denis-Folin reagent, to alcohol-water extraction – 1.2 ml of Folin-Denis reagent. The maximum value of optical density in aqueous and alcohol-aqueous extractions is observed at a wavelength of 720 nm. In alcohol-water extraction, more phenolic compounds (A = 0.8683) pass into the alcoholic water than to the aqueous one (A = 0.6346). The method used is valid and can be used for quantitative determination of the amount of phenolic compounds in fruits of sumac fluffy. To evaluate the linearity, the regression equation is calculated y = 941.67x + 0.0725 and the correlation coefficient r = 0.9895. The concentration of phenolic compounds in alcohol-water extraction was determined from the calibration graph. The average content of the sum of the phenolic compounds in terms of the gallic acid in the alcohol- water extraction was 10.04 ± 0.17%. The relative standard deviation (RSD) is 2.61%.