The paper provides an overview of the existing problems associated with the use of feed antibiotics in agricultural sectors to stimulate productivity and prevent disease. The analysis of the main sources of antibiotics entering the human food chain is carried out, the main horizontal mechanisms of transfer of genes for resistance to microorganisms at the cellular level are investigated, main threats caused by the acquisition of antibiotic resistance by the population are systematized. The paper draws conclusions about the need for preventive work with agricultural producers and the population on the competent use of dosage forms of medical and veterinary drugs, on the need for active use in agricultural production of alternative pre-, pro-, phytopreparations. The main strategic directions of the World Health Organization for the fight against antibiotic resistance in the world at all levels of its manifestation were analyzed.

At the apiary of the small innovative enterprise “Zhivprom,” Carpathian bees were studied to find out the producibility of apicultural products that are environmentally friendly due to natural concentrates of organic humic and fulvic acids as extra nutrition. For the experiment, 30 bee colonies of the Carpathian breed were selected and divided into 2 groups according to the pair-analogue principle, taking into account their origins, strength, age of queens and similar amounts of food reserves. In mid-March, 30 bees from each colony were selected from each hive to extract their rectums for morphometric measurement and determination of their excrement filling. In February and March, there was a considerable increase in the consumption of the feeding, with organic acids candy being consumed much better. The concentrates of organic acids of natural origin helped to increase the egg production of queen bees and the strength of the colony. The concentrates had no toxic effect on bees and, due to its natural origin, can be recommended as a feed additive in organic beekeeping.