Introduction. The incidence of acute cholecystitis in Ukraine, as well as worldwide, has increased in recent years and averages 6.27 per 10 thousand population. The use of laparoscopy for diagnostic purposes in patients of older age groups restrains many surgeons around the world due to the large number of negative effects of intense carboxyperitoneum. In the presence of contraindications to laparolifting cholecystectomy, ie contraindications to laparoscopic cholecystectomy, in previous works of the department it was proposed to use a new development of the department for patients with acute cholecystitis in patients of older age groups — LLСE. Objective: to improve the results of comprehensive treatment of patients suffering from destructive forms of acute cholecystitis complicated by peritonitis through the use of modern surgical minimally invasive methods. Methods: general clinical, clinical and laboratory, biochemical, instrumental, pathomorphological, statistical. Results: the use of lifting techniques of laparoscopic cholecystectomy allowed to eliminate the negative impact of intense carboxyperitoneum on patients, to avoid critical changes in hemodynamics during surgery, to exclude the development of postoperative shoulder-scapular pain, expanding the indications for endoscopic surgery. Conclusions: in destructive cholecystitis complicated by local peritonitis, the application of the developed method of lifting laparoscopic cholecystectomy revealed a significant reduction in intra- and postoperative complications compared with the group of laparoscopic cholecystectomies 5.1% and 1.7%, respectively, in the cavity. Key words: acute destructive cholecystitis, complicated with peritonitis, laparolifting cholecystectomy.