Crossflow instabilities on a 2:1 elliptic cone in hypersonic flow have been investigated in the M6QT and ACE wind tunnels at the Texas A&M National Aerothermochemistry and Hypersonics Laboratory. Experiments on a PEEK 38.1% scale model of the HIFiRE-5 flight test geometry were conducted to investigate the development of crossflow instabilities as well as to characterize the freestream and surface conditions responsible for their initial amplitudes. The freestream environment was varied not only by testing the model in both quiet and conventional tunnels but also by passively changing the fluctuation levels experienced in the conventional facility through systematic model placement. ACE freestream measurements, using a Kulite pressure transducer mounted in a pitot probe configuration and a hot-wire anemometer, indicated that fluctuation levels at the upstream model station were half those at the downstream stations. Fast-response PCB and Kulite surface mounted pressure transducers allowed examination of pressure fluctuation amplitudes and

No abstract

Introduction: Neuropsychiatric symptoms occur in 30% to 40% of patients living with systemic lupus erythematosus (SLE). Brain imaging may play a pivotal role in determining the etiology as it did for the case presented here. Methods: A new case of central nervous system (CNS) SLE is presented along with an analysis of 33 comparable cases from the scientific literature. Results: A 70-year-old female with subacute cutaneous lupus presented to a university-based geropsychiatry program after 1 year of benign visual hallucinations and several months of shuffling gait, recurrent falls, and forgetfulness. These symptoms were highly suggestive of Lewy body dementia; however, the patient’s history of basal ganglia infarct, cognitive testing demonstrating inattention and executive dysfunction, and follow-up brain imaging, which did not reveal acute findings, aligned with cerebral pathology previously attributed to vasculitis and supported the diagnosis of subcortical dementia due to SLE-CNS vasculitis. Oral prednisone 20 mg daily resolved her symptoms. Over the next 19 months, her prednisone was tapered completely and her symptoms did not return. A systematic literature search identified 33 comparable cases. Conclusion: An analysis of previously published cases suggests that extending the duration of the prednisone taper beyond 1 year may decrease the risk of later occurring neuropsychiatric symptoms in this patient population.

No abstract

No abstract