Background: Orthostatic hypotension is a condition in which blood pressure drops abnormally when a person stands up from a sitting or a lying down position. It is a sustained reduction of systolic blood pressure of at least 20mmHg or diastolic blood pressure of at least 10mmHg within three minutes of standing or a head-up tilt to at least 60 degrees on a tilt table. Orthostatic hypotension has been observed in all age groups, but it occurs more in the elderly, especially in persons who are sick and frail. The burden of Orthostatic hypotension on public health is substantial, with a prevalence of 7% to 55% in the elderly and is higher in those with risk factors. The diagnosis of orthostatic hypotension is therefore important in the treatment of elderly patients. Methods: This cross-sectional study was designed to evaluate the prevalence of orthostatic hypotension in community-dwelling elderly in Anambra State, Nigeria. The study population was a 400 persons aged 60 years and older selected by multistage sampling method. Results: The total prevalence of OH was 14.8% (n=59). The prevalence of OH was related to presence of hypertension, diabetes, raised supine systolic and raised supine diastolic BP (P ≤ 0.05). Diabetics [OR: 4.689 (95% CI: 1.121-19.984)] and those with supine diastolic hypertension [OR: 1.699 (95% CI: 0.401-7.209)] were more likely to have OH. Conclusion: The prevalence of orthostatic hypotension in 60 years and older adults in Anambra State was high and was found to be higher in hypertensives and diabetics.